MeSH Browser

MeSH Heading: Calcium Channels
Tree Number(s): D12.776.157.530.400.150; D12.776.543.550.450.150; D12.776.543.585.400.150
Unique ID: D015220
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015220
Annotation: L-, N-, P-, Q-, R-, and T-Type CALCIUM CHANNELS are available
Scope Note: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
Entry Version: CA CHANNELS
Entry Term(s): Calcium Channel; Calcium Channel Antagonist Receptor; Calcium Channel Antagonist Receptors; Calcium Channel Blocker Receptor; Calcium Channel Blocker Receptors; Ion Channel, Calcium; Ion Channels, Calcium; Receptors, Calcium Channel Antagonist; Receptors, Calcium Channel Blocker; VDCC; Voltage-Dependent Calcium Channel; Voltage-Dependent Calcium Channels
Registry Number: 0
Previous Indexing: Calcium (1979-1988); Ion Channels (1979-1988)
See Also: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases
Public MeSH Note: 89; RECEPTORS, CALCIUM CHANNEL BLOCKER was heading 1993 (was CALCIUM CHANNEL BLOCKER RECEPTOR (NM) 1983-92, was indexed under RECEPTORS, NICOTINIC 1983-92); CALCIUM CHANNEL ANTAGONIST RECEPTORS, CALCIUM CHANNEL BLOCKER RECEPTORS & RECEPTORS, CALCIUM CHANNEL ANTAGONIST were see RECEPTORS, CALCIUM CHANNEL BLOCKER 1993
Online Note: use CALCIUM CHANNELS to search RECEPTORS, CALCIUM CHANNEL BLOCKER, CALCIUM CHANNEL ANTAGONIST RECEPTORS, CALCIUM CHANNEL BLOCKER RECEPTORS & RECEPTORS, CALCIUM CHANNEL ANTAGONIST 1993; use CALCIUM CHANNELS (NM) to search RECEPTORS, CALCIUM CHANNEL BLOCKER 1983-93
History Note: 89; RECEPTORS, CALCIUM CHANNEL BLOCKER was heading 1993 (was CALCIUM CHANNEL BLOCKER RECEPTOR (NM) 1983-92); CALCIUM CHANNEL ANTAGONIST RECEPTORS, CALCIUM CHANNEL BLOCKER RECEPTORS & RECEPTORS, CALCIUM CHANNEL ANTAGONIST were see RECEPTORS, CALCIUM CHANNEL BLOCKER 1993
Entry Combination: agonists:Calcium Channel Agonists; antagonists & inhibitors:Calcium Channel Blockers
Date Established: 1989/01/01
Date of Entry: 1988/05/12
Revision Date: 2020/05/27

Entry Combination: agonists:Calcium Channel Agonists; antagonists & inhibitors:Calcium Channel Blockers
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Calcium Channels [D12.776.157.530.400.150]
        
        Calcium Channels, L-Type [D12.776.157.530.400.150.400]
        
        Calcium Channels, N-Type [D12.776.157.530.400.150.585]
        
        Calcium Channels, T-Type [D12.776.157.530.400.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.157.530.400.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.157.530.400.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.157.530.400.150.800]
        
        TRPC6 Cation Channel [D12.776.157.530.400.150.850]
        
        TRPP Cation Channels [D12.776.157.530.400.150.900]
        
        Channelrhodopsins [D12.776.157.530.400.163]
        
        Chloride Channels [D12.776.157.530.400.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.157.530.400.337]
        
        Gasdermins [D12.776.157.530.400.353]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.157.530.400.368]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Porins [D12.776.157.530.400.500]
        
        Potassium Channels [D12.776.157.530.400.600]
        
        Sodium Channels [D12.776.157.530.400.875]
        
        Transient Receptor Potential Channels [D12.776.157.530.400.901]
        
        Two-Pore Channels [D12.776.157.530.400.950]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Calcium Channels [D12.776.543.550.450.150]
        
        Calcium Channels, L-Type [D12.776.543.550.450.150.400]
        
        Calcium Channels, N-Type [D12.776.543.550.450.150.585]
        
        Calcium Channels, T-Type [D12.776.543.550.450.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.543.550.450.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.550.450.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.543.550.450.150.800]
        
        TRPC6 Cation Channel [D12.776.543.550.450.150.900]
        
        Channelrhodopsins [D12.776.543.550.450.163]
        
        Chloride Channels [D12.776.543.550.450.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.543.550.450.452]
        
        Gasdermins [D12.776.543.550.450.464]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.543.550.450.476]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Porins [D12.776.543.550.450.730]
        
        Potassium Channels [D12.776.543.550.450.750]
        
        Sodium Channels [D12.776.543.550.450.875]
        
        Two-Pore Channels [D12.776.543.550.450.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Calcium Channels [D12.776.543.585.400.150]
        
        Calcium Channels, L-Type [D12.776.543.585.400.150.400]
        
        Calcium Channels, N-Type [D12.776.543.585.400.150.585]
        
        Calcium Channels, T-Type [D12.776.543.585.400.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.543.585.400.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.585.400.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.543.585.400.150.800]
        
        TRPC6 Cation Channel [D12.776.543.585.400.150.850]
        
        TRPP Cation Channels [D12.776.543.585.400.150.900]
        
        Channelrhodopsins [D12.776.543.585.400.163]
        
        Chloride Channels [D12.776.543.585.400.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.543.585.400.452]
        
        Gasdermins [D12.776.543.585.400.464]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.543.585.400.476]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Porins [D12.776.543.585.400.730]
        
        Potassium Channels [D12.776.543.585.400.750]
        
        Sodium Channels [D12.776.543.585.400.875]
        
        Transient Receptor Potential Channels [D12.776.543.585.400.901]
        
        Two-Pore Channels [D12.776.543.585.400.950]

Calcium Channels Preferred

Concept UI: M0023383
Registry Number: 0
Scope Note: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
Terms: Calcium Channels Preferred Term
Term UI T044509
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); Calcium Channel
Term UI T044508
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994); Ion Channel, Calcium
Term UI T044510
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994); Ion Channels, Calcium
Term UI T044511
Date05/12/1988
LexicalTag NON
ThesaurusID UNK (19XX); Calcium Channel Blocker Receptor
Term UI T044512
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); VDCC
Term UI T358864
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Receptors, Calcium Channel Blocker
Term UI T044514
Date03/22/1993
LexicalTag NON
ThesaurusID NLM (1994); Calcium Channel Antagonist Receptors
Term UI T044515
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Calcium Channel Antagonist
Term UI T044516
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Calcium Channel Antagonist Receptor
Term UI T044517
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Voltage-Dependent Calcium Channels
Term UI T358863
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Voltage-Dependent Calcium Channel
Term UI T000997971
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Calcium Channel Blocker Receptors
Term UI T044513
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994)

Calcium Channels MeSH Descriptor Data 2024