MeSH Browser

MeSH Heading: Inositol 1,4,5-Trisphosphate Receptors
Tree Number(s): D12.776.157.530.400.150.760; D12.776.543.550.450.150.760; D12.776.543.585.400.150.760; D12.776.826.179
Unique ID: D053496
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053496
Scope Note: Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.
Entry Term(s): 1,4,5-INTP Receptor; INSP3 Receptor; INSP3 Receptor Type 1; INSP3 Receptor Type 2; INSP3 Receptor Type 3; IP3 Receptor; Inositol 1,4,5-Triphosphate Receptor; Inositol 1,4,5-Triphosphate Receptors; Inositol 1,4,5-Trisphosphate Receptor; Inositol 1,4,5-trisphosphate Receptor Subtype 3; Inositol 1,4,5-trisphosphate Receptor Type 1; Inositol 1,4,5-trisphosphate Receptor Type 2; Inositol 1,4,5-trisphosphate Receptor Type 3; Inositol Triphosphate Receptor; Inositol-1,4,5-Triphosphate Receptor; Receptor, Inositol-1,4,5-triphosphate; Type 1 Inositol 1,4,5-trisphosphate Receptor; Type 3 Inositol 1,4,5-trisphosphate Receptor
Public MeSH Note: 2007; INOSITOL-1,4,5-TRIPHOSPHATE RECEPTORS was indexed under CALCIUM CHANNELS & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1994-2006, & under RECEPTORS ENDOGENOUS SUBSTANCES 1986-1993
History Note: 2007(1986)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Calcium Channels [D12.776.157.530.400.150]
        
        Calcium Channels, L-Type [D12.776.157.530.400.150.400]
        
        Calcium Channels, N-Type [D12.776.157.530.400.150.585]
        
        Calcium Channels, T-Type [D12.776.157.530.400.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.157.530.400.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.157.530.400.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.157.530.400.150.800]
        
        TRPC6 Cation Channel [D12.776.157.530.400.150.850]
        
        TRPP Cation Channels [D12.776.157.530.400.150.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Calcium Channels [D12.776.543.550.450.150]
        
        Calcium Channels, L-Type [D12.776.543.550.450.150.400]
        
        Calcium Channels, N-Type [D12.776.543.550.450.150.585]
        
        Calcium Channels, T-Type [D12.776.543.550.450.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.543.550.450.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.550.450.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.543.550.450.150.800]
        
        TRPC6 Cation Channel [D12.776.543.550.450.150.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Calcium Channels [D12.776.543.585.400.150]
        
        Calcium Channels, L-Type [D12.776.543.585.400.150.400]
        
        Calcium Channels, N-Type [D12.776.543.585.400.150.585]
        
        Calcium Channels, T-Type [D12.776.543.585.400.150.720]
        
        Calcium Release Activated Calcium Channels [D12.776.543.585.400.150.740]
        
        Inositol 1,4,5-Trisphosphate Receptors [D12.776.543.585.400.150.760]
        
        Ryanodine Receptor Calcium Release Channel [D12.776.543.585.400.150.800]
        
        TRPC6 Cation Channel [D12.776.543.585.400.150.850]
        
        TRPP Cation Channels [D12.776.543.585.400.150.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Receptors, Cytoplasmic and Nuclear [D12.776.826]

Inositol 1,4,5-Trisphosphate Receptors Preferred

Concept UI: M0138366
Scope Note: Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.
Terms: Inositol 1,4,5-Trisphosphate Receptors Preferred Term
Term UI T664232
Date01/12/2006
LexicalTag NON
ThesaurusID NLM (2007); 1,4,5-INTP Receptor
Term UI T168354
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); INSP3 Receptor
Term UI T168355
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); IP3 Receptor
Term UI T168359
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); Inositol Triphosphate Receptor
Term UI T168363
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Inositol 1,4,5-Triphosphate Receptors
Term UI T168365
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Receptor, Inositol-1,4,5-triphosphate
Term UI T168368
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Inositol-1,4,5-Triphosphate Receptor
Term UI T168371
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Inositol 1,4,5-Trisphosphate Receptor
Term UI T001010118
Date03/12/2020
LexicalTag NON
ThesaurusID NLM (2021); Inositol 1,4,5-Triphosphate Receptor
Term UI T001010119
Date03/12/2020
LexicalTag NON
ThesaurusID NLM (2021)

Inositol 1,4,5-trisphosphate Receptor Type 1 Narrower

Inositol 1,4,5-trisphosphate Receptor Type 3 Narrower

Inositol 1,4,5-trisphosphate Receptor Type 2 Narrower

Inositol 1,4,5-Trisphosphate Receptors MeSH Descriptor Data 2024