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TRPC6 Cation Channel MeSH Descriptor Data 2022


MeSH Heading
TRPC6 Cation Channel
Tree Number(s)
D12.776.157.530.400.150.850
D12.776.157.530.400.901.500.500
D12.776.543.550.450.150.900
D12.776.543.585.400.150.850
D12.776.543.585.400.901.500.500
Unique ID
D000074287
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074287
Scope Note
A non-selective, calcium permeant TRPC cation channel that contains four ANKYRIN REPEATS and is activated by DIACYLGLYCEROL independently of PROTEIN KINASE C. It is expressed in placenta, lung, spleen, ovary and the small intestine, as well as by PODOCYTES in the kidney glomerulus. Mutations in the TRPC6 gene are associated with FOCAL SEGMENTAL GLOMERULOSCLEROSIS type 2.
Entry Term(s)
TRPC6
Transient Receptor Potential Cation Channel Subfamily C, Member 6
Registry Number
0
Previous Indexing
Calcium Channels (1999-2017)
TRPC Cation Channels (2006-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/02/27
TRPC6 Cation Channel Preferred
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