MeSH Browser

MeSH Heading: Gingipain Cysteine Endopeptidases
Tree Number(s): D08.811.277.656.262.500.468
Unique ID: D000080867
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080867
Scope Note: Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.
Entry Term(s): Arg-Gingipain; Argingipain; Arginine Gingipain; Gingipain; Gingipain K; Gingipain Proteases; Gingipain R; Gingipain R1; Gingipain R2; Gingipains; KGP Protease; Lys-Gingipain; Lysine Gingipain; RGP-2 Gingipain; RGPB Protein
Registry Numbers: 0; EC 3.4.22.47; EC 3.4.22.37; EC 3.4.22.37
Related Numbers: 3HJ2M2X2UM; EC 3.4.22.-; EC 3.4.22.37; EC 3.4.22.47
Previous Indexing: Cysteine Endopeptidases (1992-2019)
Public MeSH Note: 2020
History Note: 2020
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000648543
Registry Numbers: 0
Related Numbers: 3HJ2M2X2UM; EC 3.4.22.-; EC 3.4.22.37; EC 3.4.22.47
Scope Note: Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.
Terms: Gingipain Cysteine Endopeptidases Preferred Term
Term UI T000955113
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020); Gingipain
Term UI T001010045
Date03/11/2020
LexicalTag NON
ThesaurusID NLM (2021); Gingipains
Term UI T000950810
Date01/25/2019
LexicalTag NON
ThesaurusID NLM (2019); Gingipain Proteases
Term UI T000955128
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020)

Concept UI: M0226166
Registry Numbers: EC 3.4.22.47
Terms: Gingipain K Preferred Term
Term UI T000955117
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020); Lysine Gingipain
Term UI T000955118
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020); KGP Protease
Term UI T000955119
Date04/10/2019
LexicalTag ABX
ThesaurusID NLM (2020); Lys-Gingipain
Term UI T000955120
Date04/10/2019
LexicalTag ABX
ThesaurusID NLM (2020)

Concept UI: M000647273
Registry Numbers: EC 3.4.22.37
Terms: Gingipain R Preferred Term
Term UI T000951983
Date02/20/2019
LexicalTag NON
ThesaurusID NLM (2019); Arg-Gingipain
Term UI T000955116
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020); Gingipain R1
Term UI T000951980
Date02/20/2019
LexicalTag NON
ThesaurusID NLM (2019); Argingipain
Term UI T000951982
Date02/20/2019
LexicalTag NON
ThesaurusID NLM (2019); Arginine Gingipain
Term UI T000955125
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020)

Gingipain Cysteine Endopeptidases MeSH Descriptor Data 2025