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Gingipain Cysteine Endopeptidases MeSH Descriptor Data 2025


MeSH Heading
Gingipain Cysteine Endopeptidases
Tree Number(s)
D08.811.277.656.262.500.468
Unique ID
D000080867
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080867
Scope Note
Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.
Entry Term(s)
Arg-Gingipain
Argingipain
Arginine Gingipain
Gingipain
Gingipain K
Gingipain Proteases
Gingipain R
Gingipain R1
Gingipain R2
Gingipains
KGP Protease
Lys-Gingipain
Lysine Gingipain
RGP-2 Gingipain
RGPB Protein
Registry Numbers
0
EC 3.4.22.47
EC 3.4.22.37
EC 3.4.22.37
Related Numbers
3HJ2M2X2UM
EC 3.4.22.-
EC 3.4.22.37
EC 3.4.22.47
Previous Indexing
Cysteine Endopeptidases (1992-2019)
Public MeSH Note
2020
History Note
2020
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2020/05/27
Gingipain Cysteine Endopeptidases Preferred
Gingipain K Narrower
Gingipain R Narrower
Gingipain R2 Narrower
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