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Tryptophan Hydroxylase MeSH Descriptor Data 2025


MeSH Heading
Tryptophan Hydroxylase
Tree Number(s)
D08.811.682.690.708.870
Unique ID
D014365
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014365
Scope Note
An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
Entry Term(s)
Tryptophan Monooxygenase
Registry Numbers
EC 1.14.16.4
CAS Type 1 Name
L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating)
Previous Indexing
Hydroxylases (1966-1972)
See Also
Tryptophan Oxygenase
Public MeSH Note
78; was see under HYDROXYLASES 1975-77
History Note
78(73); was see under HYDROXYLASES 1975-77
Date Established
1978/01/01
Date of Entry
1999/01/01
Revision Date
2004/07/07
Tryptophan Hydroxylase Preferred
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