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AlkB Homolog 8, tRNA Methyltransferase MeSH Descriptor Data 2022


MeSH Heading
AlkB Homolog 8, tRNA Methyltransferase
Tree Number(s)
D08.811.682.690.416.139.984
D08.811.913.555.500.925.500
Unique ID
D000071503
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071503
Scope Note
A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).
Entry Term(s)
Alkylated DNA Repair Protein Alkb Homolog 8
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8
Registry Number
EC 1.14.11.-
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/04/15
AlkB Homolog 8, tRNA Methyltransferase Preferred
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