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AlkB Homolog 5, RNA Demethylase MeSH Descriptor Data 2025


MeSH Heading
AlkB Homolog 5, RNA Demethylase
Tree Number(s)
D08.811.074.062.937
D08.811.682.662.582.207
D08.811.682.690.416.139.968
Unique ID
D000071502
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071502
Scope Note
A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.
Entry Term(s)
Alkylated DNA Repair Protein AlkB Homolog 5
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5
RNA Demethylase ALKBH5
Registry Numbers
EC 1.14.11.-
Previous Indexing
Dioxygenases (2011-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/04/15
AlkB Homolog 5, RNA Demethylase Preferred
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