MeSH Browser

MeSH Heading: Sarcosine Dehydrogenase
Tree Number(s): D08.811.682.662.582.550
Unique ID: D050892
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050892
Scope Note: A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
Entry Term(s): Monomethylglycine Dehydrogenase; Sarcosine N-Demethylase
Registry Numbers: EC 1.5.8.3
Related Numbers: 37228-65-2
Public MeSH Note: 2006; SARCOSINE DEHYDROGENASE was indexed under OXIDOREDUCTASES, N-DEMETHYLATING 1976-2004, & under SARCOSINE 1976-1982
History Note: 2006(1976); use OXIDOREDUCTASES, N-DEMETHYLATING, & SARCOSINE 1976-1979
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0078933
Registry Numbers: EC 1.5.8.3
Related Numbers: 37228-65-2
Scope Note: A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
Terms: Sarcosine Dehydrogenase Preferred Term
Term UI T108936
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Monomethylglycine Dehydrogenase
Term UI T625853
Date12/23/2004
LexicalTag NON
ThesaurusID NLM (2006); Sarcosine N-Demethylase
Term UI T625852
Date12/23/2004
LexicalTag NON
ThesaurusID NLM (2006)

Sarcosine Dehydrogenase MeSH Descriptor Data 2025