An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
Entry Term(s)
6,7-Dihydropteridine Reductase
CAS Type 1 Name
NAD(P)H:6,7-dihydropteridine oxidoreductase
Previous Indexing
NADH, NADPH Oxidoreductases (1973-1974)
Pteridines (1973-1974)
Public MeSH Note
91; was see under NADH, NADPH OXIDOREDUCTASES 1975-90
History Note
91(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-90
An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.