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Dihydropteridine Reductase MeSH Descriptor Data 2025


MeSH Heading
Dihydropteridine Reductase
Tree Number(s)
D08.811.682.662.582.361
Unique ID
D004093
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004093
Scope Note
An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
Entry Term(s)
6,7-Dihydropteridine Reductase
Registry Numbers
EC 1.5.1.34
CAS Type 1 Name
NAD(P)H:6,7-dihydropteridine oxidoreductase
Previous Indexing
NADH, NADPH Oxidoreductases (1973-1974)
Pteridines (1973-1974)
Public MeSH Note
91; was see under NADH, NADPH OXIDOREDUCTASES 1975-90
History Note
91(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-90
Entry Combination
deficiency:Phenylketonurias
Date Established
1991/01/01
Date of Entry
1974/11/27
Revision Date
2015/06/22
Dihydropteridine Reductase Preferred
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