MeSH Browser

MeSH Heading: Vasopeptidase Inhibitors
Tree Number(s): D27.505.519.389.745.085.500
Unique ID: D000075563
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000075563
Scope Note: A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.
Entry Term(s): ACE-NEP Inhibitors; NEP-ACE Inhibitors; Vasopeptidase Inhibitor
Registry Numbers: 0
Previous Indexing: Angiotensin-Converting Enzyme Inhibitors (1999-2017); Neprilysin/antagonists and inhibitors (1999-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analogs & derivatives (AA)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M000630678
Registry Numbers: 0
Scope Note: A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.
Terms: Vasopeptidase Inhibitors Preferred Term
Term UI T000922762
Date04/27/2017
LexicalTag NON
ThesaurusID NLM (2018); Vasopeptidase Inhibitor
Term UI T001090486
Date10/23/2020
LexicalTag NON
ThesaurusID NLM (2022); ACE-NEP Inhibitors
Term UI T000922765
Date04/27/2017
LexicalTag NON
ThesaurusID NLM (2018); NEP-ACE Inhibitors
Term UI T000922766
Date04/27/2017
LexicalTag NON
ThesaurusID NLM (2018)

Vasopeptidase Inhibitors MeSH Descriptor Data 2025