MeSH Browser

MeSH Heading: Imipramine
Tree Number(s): D03.633.300.240.485
Unique ID: D007099
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007099
Scope Note: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
Entry Term(s): 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)-N,N-dimethyl-1-propanamine (1:2); Imidobenzyle; Imipramine Hydrochloride; Imipramine Monohydrochloride; Imipramine Pamoate; Imizin; Janimine; Melipramine; Norchlorimipramine; Pryleugan; Tofranil
Pharm Action: Antidepressive Agents, Tricyclic
Adrenergic Uptake Inhibitors
Related Numbers: 113-52-0; 50-49-7; BKE5Q1J60U; MC34P30298
CAS Type 1 Name: 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-
NLM Classification #: QV 77.5
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0011056
Related Numbers: 113-52-0; 50-49-7; BKE5Q1J60U; MC34P30298
Scope Note: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
Terms: Imipramine Preferred Term
Term UI T021232
Date01/01/1999
LexicalTag NON
ThesaurusID; Imidobenzyle
Term UI T021231
Date12/30/1976
LexicalTag NON
ThesaurusID UNK (19XX); Norchlorimipramine
Term UI T021234
Date10/09/1986
LexicalTag NON
ThesaurusID UNK (19XX)

Imipramine MeSH Descriptor Data 2024