MeSH Browser

MeSH Heading: Lofepramine
Tree Number(s): D03.633.300.240.520
Unique ID: D008127
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008127
Scope Note: A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.
Entry Term(s): Deftan; Feprapax; Gamanil; Gamonil; Leo 640; Lofepramine Hydrochloride; Lomont; Lopramine
Pharm Action: Antidepressive Agents, Tricyclic
Registry Numbers: OCA4JT7PAW; Z24K96F991; 0
Related Numbers: 23047-25-8; 26786-32-3; Z24K96F991
CAS Type 1 Name: Ethanone, 1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)-
NLM Classification #: QV 77.5
Previous Indexing: Dibenzazepines (1969-1978)
Public MeSH Note: 91; was see under DIBENZAZEPINES 1979-90
History Note: 91(79); was see under DIBENZAZEPINES 1979-90
Date Established: 1991/01/01
Date of Entry: 1978/03/20
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Lofepramine MeSH Descriptor Data 2025