NLM Logo

Mice, Inbred mdx MeSH Descriptor Data 2022


MeSH Heading
Mice, Inbred mdx
Tree Number(s)
B01.050.050.199.520.520.420.500
B01.050.150.900.649.313.992.635.505.500.400.420.500
B01.050.150.900.649.313.992.635.505.500.550.265
Unique ID
D018101
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018101
Annotation
NIM with no qualifiers when experimental animal
Scope Note
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
Entry Term(s)
Mice, mdx
Mouse, Inbred mdx
Mouse, mdx
Previous Indexing
Mice, Inbred C57BL (1984-1993)
Mice, Mutant Strains (1984-1993)
See Also
Muscular Dystrophies
Public MeSH Note
94
History Note
94
Date Established
1994/01/01
Date of Entry
1993/06/03
Revision Date
2020/09/02
Mice, Inbred mdx Preferred
page delivered in 0.692s