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Multiple Endocrine Neoplasia Type 1 MeSH Descriptor Data 2022


MeSH Heading
Multiple Endocrine Neoplasia Type 1
Tree Number(s)
C04.588.322.400.500
C04.651.600.500
C04.700.630.500
C16.320.700.630.500
C19.344.400.500
Unique ID
D018761
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018761
Annotation
coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent
Scope Note
A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).
Entry Version
MULTIPLE ENDOCRINE NEOPL TYPE 1
Entry Term(s)
Multiple Endocrine Neoplasia Type I
Multiple Endocrine Neoplasms Type 1
Neoplasia, Multiple Endocrine Type 1
Neoplasms, Multiple Endocrine Type 1
Neoplasms, Multiple Endocrine Type I
Wermer Syndrome
Previous Indexing
Multiple Endocrine Neoplasia (1972-1994)
Public MeSH Note
95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94
Online Note
use MULTIPLE ENDOCRINE NEOPLASIA to search MEA I, MEN I, & WERMER SYNDROME 1983-94
History Note
95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94
Date Established
1995/01/01
Date of Entry
1994/05/23
Revision Date
2017/02/24
Multiple Endocrine Neoplasia Type 1 Preferred
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