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Integrin alpha6beta4 MeSH Descriptor Data 2022


MeSH Heading
Integrin alpha6beta4
Tree Number(s)
D12.776.543.750.705.408.460.170
D12.776.543.750.705.876.750
Unique ID
D039161
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D039161
Scope Note
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Entry Term(s)
A9 Antigen
Integrin alpha(6),beta(4)
Laminin-5 Receptor (alpha6beta4 Integrin)
TSP-180
Tumor Specific Protein-180 Complex
alpha(6)beta(4) Epithelial Integrin
alpha(6)beta(4) Integrin
alpha6 beta4 Integrin
Registry Number
0
Previous Indexing
Antigens, Surface (1988-2002)
Integrins (1988-2002)
Public MeSH Note
2003; INTEGRIN ALPHA6BETA4 was indexed under INTEGRINS; & ANTIGENS, SURFACE 1988-2002.
History Note
2003; use INTEGRIN ALPHA6BETA4 (NM) 1988-2002
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2013/07/09
Integrin alpha6beta4 Preferred
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