MeSH Browser

MeSH Heading: Integrin alpha3beta1
Tree Number(s): D12.776.543.750.685.300; D12.776.543.750.705.408.850.249; D12.776.543.750.705.876.311
Unique ID: D039201
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039201
Scope Note: Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.
Entry Term(s): CD49c-CD29; Epiligrin Receptor; Galactoprotein b3; Gap b3; Integrin alpha(3)beta(1); Laminin-5 Receptor (alpha3beta1 integrin); VLA-3; alpha3beta1 Epiligrin Receptor; alpha3beta1 Integrin
Previous Indexing: Integrins (1992-2002)
Public MeSH Note: 2003; INTEGRIN ALPHA3BETA1 was indexed under INTEGRINS 1992-2002
History Note: 2003; use INTEGRIN ALPHA3BETA1 (NM) 1992-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2016/06/17

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Collagen [D12.776.543.750.685]
        
        Discoidin Domain Receptors [D12.776.543.750.685.050]
        
        Integrin alpha1beta1 [D12.776.543.750.685.100]
        
        Integrin alpha2beta1 [D12.776.543.750.685.200]
        
        Integrin alpha3beta1 [D12.776.543.750.685.300]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Very Late Antigen [D12.776.543.750.705.408.850]
        
        Integrin alpha1beta1 [D12.776.543.750.705.408.850.099]
        
        Integrin alpha2beta1 [D12.776.543.750.705.408.850.199]
        
        Integrin alpha3beta1 [D12.776.543.750.705.408.850.249]
        
        Integrin alpha4beta1 [D12.776.543.750.705.408.850.299]
        
        Integrin alpha5beta1 [D12.776.543.750.705.408.850.349]
        
        Integrin alpha6beta1 [D12.776.543.750.705.408.850.674]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Laminin [D12.776.543.750.705.876]
        
        Integrin alpha1beta1 [D12.776.543.750.705.876.249]
        
        Integrin alpha2beta1 [D12.776.543.750.705.876.280]
        
        Integrin alpha3beta1 [D12.776.543.750.705.876.311]
        
        Integrin alpha5beta1 [D12.776.543.750.705.876.374]
        
        Integrin alpha6beta1 [D12.776.543.750.705.876.500]
        
        Integrin alpha6beta4 [D12.776.543.750.705.876.750]

Integrin alpha3beta1 Preferred

Concept UI: M0199874
Scope Note: Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.
Terms: Integrin alpha3beta1 Preferred Term
Term UI T229879
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Integrin alpha(3)beta(1)
Term UI T229877
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Laminin-5 Receptor (alpha3beta1 integrin)
Term UI T229878
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Epiligrin Receptor
Term UI T229875
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); CD49c-CD29
Term UI T229870
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); VLA-3
Term UI T229872
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); alpha3beta1 Epiligrin Receptor
Term UI T229873
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); alpha3beta1 Integrin
Term UI T229874
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Galactoprotein b3
Term UI T229876
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Gap b3
Term UI T229871
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003)

Integrin alpha3beta1 MeSH Descriptor Data 2024