NLM Logo

Integrin alpha2beta1 MeSH Descriptor Data 2022


MeSH Heading
Integrin alpha2beta1
Tree Number(s)
D12.776.395.550.625.298
D12.776.543.550.625.298
D12.776.543.750.685.200
D12.776.543.750.705.408.530.249
D12.776.543.750.705.408.850.199
D12.776.543.750.705.675.352
D12.776.543.750.705.876.280
Unique ID
D038982
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D038982
Scope Note
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
Entry Term(s)
CD49b-CD29
Glycoprotein Ia-IIa
Platelet Membrane Glycoprotein Heterodimer Ia-IIa
VLA-2
Very Late Antigen-2
alpha2beta1Integrin
Registry Number
0
Previous Indexing
Collagen Receptors (1991-2002)
Integrins (1994-2002)
Public MeSH Note
2003; INTEGRIN ALPHA2BETA1 was indexed under INTEGRINS 1994-2002
History Note
2003; for VLA-2 use COLLAGEN RECEPTORS (NM) 1991-2002; for PLATELET MEMBRANE GLYCOPROTEIN HETERODIMER IA-IIA use COLLAGEN RECEPTORS (NM) 1992-2000; for INTEGRIN ALPHA2BETA1 & CD49B-CD29 use COLLAGEN RECEPTORS (NM) 1994-2002; for ALPHA2BETA1INTEGRIN use COLLAGEN RECEPTORS (NM) 2001-2002
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2016/06/17
Integrin alpha2beta1 Preferred
page delivered in 0.147s