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Integrin alpha1beta1 MeSH Descriptor Data 2022


MeSH Heading
Integrin alpha1beta1
Tree Number(s)
D12.776.543.750.685.100
D12.776.543.750.705.408.850.099
D12.776.543.750.705.876.249
Unique ID
D039222
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D039222
Scope Note
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.
Entry Term(s)
CD49a-CD29
Integrin alpha(1)beta(1)
VLA-1
alpha1beta1 Integrin
Registry Number
0
Previous Indexing
Integrins (1994-2002)
Public MeSH Note
2003; INTEGRIN ALPHA1BETA1 was indexed under INTEGRINS 1994-2002
History Note
2003; use INTEGRIN ALPHA1BETA1 (NM) 1994-2002
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2016/06/17
Integrin alpha1beta1 Preferred
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