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Core Binding Factor alpha Subunits MeSH Descriptor Data 2022


MeSH Heading
Core Binding Factor alpha Subunits
Tree Number(s)
D12.776.930.155.200
Unique ID
D050657
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050657
Scope Note
A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
Entry Term(s)
Acute Myeloid Leukemia Proteins
Core Binding Factor alpha Proteins
PEBP2A Transcription Factors
Polyomavirus Enhancer A Binding Protein 2
Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
Runt Domain Factor
Runx Proteins
Registry Number
0
Previous Indexing
DNA-Binding Proteins (1987-2005)
Neoplasm Proteins (1997-2005)
Transcription Factors (1987-2005)
Public MeSH Note
2006; POLYOMAVIRUS ENHANCER A BINDING PROTEIN 2 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1987-2005, & under NEOPLASM PROTEINS 1997-2005; RUNT DOMAIN FACTOR was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 2000-2005, & under NEOPLASM PROTEINS 2000-2005
History Note
2006(1987)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2013/07/09
Core Binding Factor alpha Subunits Preferred
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