MeSH Browser

MeSH Heading: Core Binding Factor Alpha 3 Subunit
Tree Number(s): D12.776.930.155.200.300
Unique ID: D050677
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050677
Annotation: see SCR for organism-specific terms
Scope Note: A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain.
Entry Term(s): AML2 Protein; Acute Myeloid Leukemia 2 Protein; CBFA3 Protein; Core-Binding Factor Alpha 3 Protein; PEBP2A3 Protein; Runt Domain Transcription Factor AML-2; Runt-Related Transcription Factor 3 Protein; Runx3 Protein
Previous Indexing: DNA-Binding Proteins (2001-2005); Transcription Factors (2001-2005)
Public MeSH Note: 2006; RUNX3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 2001-2005
History Note: 2006(2001)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0399600
Scope Note: A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain.
Terms: Core Binding Factor Alpha 3 Subunit Preferred Term
Term UI T623789
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); Acute Myeloid Leukemia 2 Protein
Term UI T622211
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006); AML2 Protein
Term UI T575099
Date03/02/2004
LexicalTag ABX
ThesaurusID NLM (2006); CBFA3 Protein
Term UI T575100
Date03/02/2004
LexicalTag ABX
ThesaurusID NLM (2006); Core-Binding Factor Alpha 3 Protein
Term UI T622212
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006); PEBP2A3 Protein
Term UI T622213
Date12/07/2004
LexicalTag ABX
ThesaurusID NLM (2006); Runt Domain Transcription Factor AML-2
Term UI T497040
Date06/06/2002
LexicalTag ABX
ThesaurusID NLM (2006); Runt-Related Transcription Factor 3 Protein
Term UI T622214
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006); Runx3 Protein
Term UI T463226
Date09/25/2001
LexicalTag ACX
ThesaurusID NLM (2006)

Core Binding Factor Alpha 3 Subunit MeSH Descriptor Data 2024