MeSH Browser

MeSH Heading: Core Binding Factor Alpha 1 Subunit
Tree Number(s): D12.776.930.155.200.100
Unique ID: D050659
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050659
Annotation: see SCR for organism-specific terms
Scope Note: A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
Entry Term(s): AML3 Transcription Factor; Acute Myeloid Leukemia 3 Protein; CBFA-1 Protein; CBFA1 Protein; CBFalpha Runt Domain Transcription Factor 1; CBFalpha1 Protein; Osf2 Transcription Factor; PEBP2alphaA Protein; Runx2 Protein; SEF1 Protein; SL3-3 Enhancer Factor 1
Previous Indexing: Neoplasm Proteins (1997-2005); Transcription Factors (1997-2005)
Public MeSH Note: 2006; RUNX2 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1997-2005
History Note: 2006(1997)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Core Binding Factors [D12.776.930.155]
      - Core Binding Factor alpha Subunits [D12.776.930.155.200]
        
        Core Binding Factor Alpha 1 Subunit [D12.776.930.155.200.100]
        
        Core Binding Factor Alpha 2 Subunit [D12.776.930.155.200.200]
        
        Core Binding Factor Alpha 3 Subunit [D12.776.930.155.200.300]

Core Binding Factor Alpha 1 Subunit Preferred

Concept UI: M0276678
Scope Note: A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
Terms: Core Binding Factor Alpha 1 Subunit Preferred Term
Term UI T623663
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); AML3 Transcription Factor
Term UI T306677
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); CBFA-1 Protein
Term UI T575098
Date03/02/2004
LexicalTag ABX
ThesaurusID NLM (2006); CBFA1 Protein
Term UI T306679
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); CBFalpha Runt Domain Transcription Factor 1
Term UI T306680
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); CBFalpha1 Protein
Term UI T306681
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Acute Myeloid Leukemia 3 Protein
Term UI T622108
Date12/06/2004
LexicalTag NON
ThesaurusID NLM (2006); PEBP2alphaA Protein
Term UI T241903
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Runx2 Protein
Term UI T421583
Date08/12/2000
LexicalTag NON
ThesaurusID NLM (2006); SEF1 Protein
Term UI T483340
Date02/25/2002
LexicalTag ABX
ThesaurusID NLM (2006); SL3-3 Enhancer Factor 1
Term UI T241904
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Osf2 Transcription Factor
Term UI T306682
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006)

Core Binding Factor Alpha 1 Subunit MeSH Descriptor Data 2024