Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome MeSH Descriptor Data 2025
A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.
Entry Term(s)
Anapc7
Apc7 Subunit, Anaphase-Promoting Complex
Registry Numbers
0
Previous Indexing
Cell Cycle Proteins (1996-2003)
Ligases (1996-2003)
Ubiquitin-Protein Ligase Complexes (2004-2013)
Public MeSH Note
2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013
A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.