MeSH Browser

MeSH Heading: Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome
Tree Number(s): D08.811.464.938.750.092.625; D12.776.167.024.625
Unique ID: D064197
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064197
Scope Note: Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.
Entry Term(s): Anapc10; Apc10 Subunit, Anaphase-Promoting Complex
Previous Indexing: Cell Cycle Proteins (1996-2013); Ligases (1996-2003); Ubiquitin-Protein Ligase Complexes (2004-2013)
Public MeSH Note: 2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome MeSH Descriptor Data 2024