Fatty Acid Synthases MeSH Descriptor Data 2026

MeSH Heading: Fatty Acid Synthases
Tree Number(s): D08.811.277.352.897.387; D08.811.520.241.300.287; D08.811.682.047.820.196.500; D08.811.913.050.134.029.500; D08.811.913.050.170.500
Unique ID: D064429
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064429
Scope Note: Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.
Entry Term(s): Fatty Acid Synthase; Fatty Acid Synthetases
Registry Numbers: EC 2.3.1.85
Related Numbers: EC 1.1.1.100; EC 2.3.1.38; EC 2.3.1.39; EC 2.3.1.41; EC 3.1.2.14; EC 4.2.1.59
Public MeSH Note: 2014; see FATTY ACID SYNTHETASE COMPLEX 1972-2013
History Note: 2014
Date Introduced: 2014/01/01
Last Updated: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Thiolester Hydrolases [D08.811.277.352.897]
        
        Acetyl-CoA Hydrolase [D08.811.277.352.897.075]
        
        Fatty Acid Synthases [D08.811.277.352.897.387]
        
        Fatty Acid Synthase, Type I [D08.811.277.352.897.387.100]
        
        Fatty Acid Synthase, Type II [D08.811.277.352.897.387.200]
        
        Hydroxyacylglutathione Hydrolase [D08.811.277.352.897.544]
        
        Palmitoyl-CoA Hydrolase [D08.811.277.352.897.700]
        
        Ubiquitin Thiolesterase [D08.811.277.352.897.850]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Lyases [D08.811.520]
    - Carbon-Oxygen Lyases [D08.811.520.241]
      - Hydro-Lyases [D08.811.520.241.300]
        
        Aconitate Hydratase [D08.811.520.241.300.050]
        
        Carbonic Anhydrases [D08.811.520.241.300.150]
        
        Cystathionine beta-Synthase [D08.811.520.241.300.200]
        
        Enoyl-CoA Hydratase [D08.811.520.241.300.250]
        
        Enoyl-CoA Hydratase 2 [D08.811.520.241.300.275]
        
        Fatty Acid Synthases [D08.811.520.241.300.287]
        
        Fatty Acid Synthase, Type I [D08.811.520.241.300.287.099]
        
        Fatty Acid Synthase, Type II [D08.811.520.241.300.287.200]
        
        Fumarate Hydratase [D08.811.520.241.300.300]
        
        Phosphopyruvate Hydratase [D08.811.520.241.300.500]
        
        Porphobilinogen Synthase [D08.811.520.241.300.550]
        
        Prephenate Dehydratase [D08.811.520.241.300.600]
        
        Propanediol Dehydratase [D08.811.520.241.300.650]
        
        Tryptophan Synthase [D08.811.520.241.300.850]
        
        Urocanate Hydratase [D08.811.520.241.300.900]
        
        Uroporphyrinogen III Synthetase [D08.811.520.241.300.950]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Alcohol Oxidoreductases [D08.811.682.047]
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
        
        3-Oxoacyl-(Acyl-Carrier-Protein) Reductase [D08.811.682.047.820.196]
        
        Fatty Acid Synthases [D08.811.682.047.820.196.500]
        
        Fatty Acid Synthase, Type I [D08.811.682.047.820.196.500.099]
        
        Fatty Acid Synthase, Type II [D08.811.682.047.820.196.500.200]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Acyltransferases [D08.811.913.050]
      - Acetyltransferases [D08.811.913.050.134]
        
        Acyl-Carrier Protein S-Acetyltransferase [D08.811.913.050.134.029]
        
        Fatty Acid Synthases [D08.811.913.050.134.029.500]
        
        Fatty Acid Synthase, Type I [D08.811.913.050.134.029.500.100]
        
        Fatty Acid Synthase, Type II [D08.811.913.050.134.029.500.200]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Acyltransferases [D08.811.913.050]
      - Acyl-Carrier Protein S-Malonyltransferase [D08.811.913.050.170]
        
        Fatty Acid Synthases [D08.811.913.050.170.500]
        
        Fatty Acid Synthase, Type I [D08.811.913.050.170.500.100]
        
        Fatty Acid Synthase, Type II [D08.811.913.050.170.500.200]

Fatty Acid Synthases Preferred

Concept UI: M0581832
Registry Numbers: EC 2.3.1.85
Related Numbers: EC 1.1.1.100; EC 2.3.1.38; EC 2.3.1.39; EC 2.3.1.41; EC 3.1.2.14; EC 4.2.1.59
Scope Note: Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.
Terms: Fatty Acid Synthases Preferred Term
Term UI T838053
Date03/01/2013
LexicalTag NON
ThesaurusID NLM (2014); Fatty Acid Synthase
Term UI T000996307
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Fatty Acid Synthetases
Term UI T838054
Date03/01/2013
LexicalTag NON
ThesaurusID NLM (2014)

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