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Interferon Regulatory Factor-3 MeSH Descriptor Data 2025
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Entry Term(s)
IFN-Regulatory Factor 3
IRF-3 Transcription Factor
Registry Numbers
0
Public MeSH Note
2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.