Interferon Regulatory Factor-3 MeSH Descriptor Data 2024

MeSH Heading: Interferon Regulatory Factor-3
Tree Number(s): D12.644.360.024.302.374; D12.776.157.057.050.374; D12.776.260.504.374; D12.776.476.024.385.374; D12.776.744.562; D12.776.930.332.374
Unique ID: D050838
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050838
Scope Note: An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Entry Term(s): IFN-Regulatory Factor 3; IRF-3 Transcription Factor
Public MeSH Note: 2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005
History Note: 2006(1996)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - Interferon Regulatory Factors [D12.644.360.024.302]
        
        Interferon Regulatory Factor-1 [D12.644.360.024.302.124]
        
        Interferon Regulatory Factor-2 [D12.644.360.024.302.249]
        
        Interferon Regulatory Factor-3 [D12.644.360.024.302.374]
        
        Interferon Regulatory Factor-7 [D12.644.360.024.302.437]
        
        Interferon-Stimulated Gene Factor 3, gamma Subunit [D12.644.360.024.302.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Interferon Regulatory Factors [D12.776.157.057.050]
        
        Interferon Regulatory Factor-1 [D12.776.157.057.050.124]
        
        Interferon Regulatory Factor-2 [D12.776.157.057.050.249]
        
        Interferon Regulatory Factor-3 [D12.776.157.057.050.374]
        
        Interferon Regulatory Factor-7 [D12.776.157.057.050.437]
        
        Interferon-Stimulated Gene Factor 3, gamma Subunit [D12.776.157.057.050.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Interferon Regulatory Factors [D12.776.260.504]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Interferon Regulatory Factors [D12.776.476.024.385]
        
        Interferon Regulatory Factor-1 [D12.776.476.024.385.124]
        
        Interferon Regulatory Factor-2 [D12.776.476.024.385.249]
        
        Interferon Regulatory Factor-3 [D12.776.476.024.385.374]
        
        Interferon Regulatory Factor-7 [D12.776.476.024.385.437]
        
        Interferon-Stimulated Gene Factor 3, gamma Subunit [D12.776.476.024.385.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Phosphoproteins [D12.776.744]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Interferon Regulatory Factors [D12.776.930.332]

Interferon Regulatory Factor-3 Preferred

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