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Matrix Metalloproteinase 1 MeSH Descriptor Data 2025


MeSH Heading
Matrix Metalloproteinase 1
Tree Number(s)
D08.811.277.656.300.480.205.351
D08.811.277.656.300.480.525.700.100
D08.811.277.656.675.374.205.351
D08.811.277.656.675.374.525.700.100
D12.776.467.836.100
Unique ID
D020781
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020781
Scope Note
A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.
Entry Term(s)
Interstitial Collagenase
MMP-1 Metalloproteinase
MMP1 Metalloproteinase
Matrix Metalloproteinase-1
Pro-Matrix Metalloproteinase-1
Promatrixmetalloproteinase-1
proMMP-1
Registry Numbers
EC 3.4.24.7
EC 3.4.24.-
Previous Indexing
Collagenases (1991-1999)
Public MeSH Note
2007; see INTERSTITIAL COLLAGENASE 2000-2006; PRO-MATRIX METALLOPROTEINASE 1 was indexed under ENZYME PRECURSORS & COLLAGENASES 1995-2006
History Note
2007(2000)
Entry Combination
antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established
2000/01/01
Date of Entry
1999/11/08
Revision Date
2021/05/21
Matrix Metalloproteinase 1 Preferred
Pro-Matrix Metalloproteinase-1 Narrower
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