MeSH Browser

MeSH Heading: Lactose Synthase
Tree Number(s): D05.500.299; D08.811.913.400.450.400.500
Unique ID: D007788
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007788
Scope Note: An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.
Entry Term(s): Lactose Synthetase; N-Acetylgucosamide 1-4 beta Galactosyl Transferase
Registry Number: EC 2.4.1.22
Related Numbers: 9030-11-9
CAS Type 1 Name: UDPgalactose:D-glucose 4-beta-D-galactosyltransferase
Previous Indexing: Glucosyltransferases (1966-1971); Lactation (1966-1971); Ligases (1966-1971); Transferases (1966-1971)
Public MeSH Note: 92; was LACTOSE SYNTHETASE 1974-91
Online Note: use LACTOSE SYNTHASE to search LACTOSE SYNTHETASE 1972-91 (as Prov 1972-73)
History Note: 92: was LACTOSE SYNTHETASE 1972-91 (Prov 1972-73)
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Lactose Synthase MeSH Descriptor Data 2024