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Proprotein Convertases MeSH Descriptor Data 2024


MeSH Heading
Proprotein Convertases
Tree Number(s)
D08.811.277.656.837
Unique ID
D043484
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D043484
Scope Note
Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.
Entry Term(s)
POMC Convertase
POMC Enzyme
POMC-Converting Enzyme
Pro-Opiocortin Converting Enzyme
Pro-Opiocortin Converting Protease
Pro-Opiomelanocortin Converting Enzyme
Prohormone Convertase
Prohormone Convertases
Proopiomelanocortin Convertase
Proprotein Convertase
Proprotein Convertase, Subtilisin-Kexin Family
Proprotein Convertases, Subtilisin-Kexin Family
Subtilisin-Like Proprotein Convertases
Registry Number
EC 3.4.21.-
Related Numbers
EC 3.4.21.-
EC 3.4.21.61
EC 3.4.23.17
Previous Indexing
Aspartic Endopeptidases (1994-2003)
Peptide Peptidohydrolases (1982-1993)
Subtilisins (2002-2003)
Public MeSH Note
2004; PROPROTEIN COVERTASES was indexed under SUBSTILISINS 2002-2003; PRO-OPIOMELANOCORTIN CONVERTING ENZYME was indexed under ASPARTIC ENDOPEPTIDASES 1994-2003, under PEPTIDE PEPTIDOHYDROLASES 1982-1993
History Note
2004; use PROPROTEIN CONVERTASES (NM) 2002-2003; for PRO-OPIOMELANOCORTIN CONVERTING ENZYME use PROPROTEIN CONVERTASES (NM) 1982-2003
Date Established
2004/01/01
Date of Entry
2003/07/22
Revision Date
2016/06/30
Proprotein Convertases Preferred
Prohormone Convertases Narrower
Proprotein Convertases, Subtilisin-Kexin Family Narrower
Subtilisin-Like Proprotein Convertases Narrower
Pro-Opiomelanocortin Converting Enzyme Narrower
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