A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.
Entry Term(s)
Procollagen C-Endopeptidase
Registry Numbers
EC 3.4.24.19
Public MeSH Note
2009; BONE MORPHOGENETIC PROTEIN 1 was inedxed under METALLOENDPEPTIDASES & BONE MORPHOGENETIC PROTEINS 1996-2008, under PEPTIDE PEPTIDOHYDROLASES 1978-1995, & under PROCOLLAGEN 1978-1982
A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.
