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Cytochrome P-450 CYP1A1 MeSH Descriptor Data 2023


MeSH Heading
Cytochrome P-450 CYP1A1
Tree Number(s)
D08.244.453.005.332
D08.244.453.100.500
D08.811.682.690.708.170.010.277
D08.811.682.690.708.170.020.500
D12.776.422.220.453.010.332
D12.776.422.220.453.100.500
Unique ID
D019363
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019363
Annotation
do not confuse with other cytochrome P-450 CYP's
Scope Note
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Entry Term(s)
7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1
CYP1A1 Protein
Cytochrome P450 IA1
EROD
Ethoxyresorufin Dealkylase
Ethoxyresorufin O-Deethylase
Ethylresorufin O-Deethylase
Registry Number
EC 1.14.14.1
Previous Indexing
Cytochrome P-450 (1982-1996)
Oxazines (1979-1981)
Oxidoreductases (1980-1996)
Public MeSH Note
97; ETHOXYRESORUFIN O-DEETHYLASE was indexed under CYTOCHROME P-450 1982-96, OXIDOREDUCTASES 1980-96, & OXAZINES 1979-81
Online Note
use CYTOCHROME P-450 CYP1A1 (NM) to search ETHOXYRESORUFIN O-DEETHYLASE 1980-96
History Note
97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96
Date Established
1997/01/01
Date of Entry
1996/06/24
Revision Date
2016/05/27
Cytochrome P-450 CYP1A1 Preferred
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