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Cytochrome P-450 CYP2B6 MeSH Descriptor Data 2022


MeSH Heading
Cytochrome P-450 CYP2B6
Tree Number(s)
D08.244.453.005.575
D08.244.453.491.344
D08.811.682.690.708.170.010.575
D08.811.682.690.708.170.450.344
D12.776.422.220.453.010.575
D12.776.422.220.453.491.344
Unique ID
D065702
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D065702
Scope Note
A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.
Entry Term(s)
1,4-Cineole 2-exo-Monooxygenase
CYP2B6
CYPIIB6
Cytochrome P450 2B6
Registry Number
EC 1.14.14.1
Public MeSH Note
2015; CYTOCHROME P-450 CYP2B6 was indexed under ARYL HYDROCARBON HYDROXYLASES 1997-2014
History Note
2015
Entry Combination
antagonists & inhibitors:Cytochrome P-450 CYP2B6 Inhibitors
Date Established
2015/01/01
Date of Entry
2014/06/26
Revision Date
2016/05/27
Cytochrome P-450 CYP2B6 Preferred
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