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Cytochrome P-450 CYP2C8 MeSH Descriptor Data 2022


MeSH Heading
Cytochrome P-450 CYP2C8
Tree Number(s)
D08.244.453.005.590
D08.244.453.491.368
D08.811.682.690.708.170.010.590
D08.811.682.690.708.170.450.360
D12.776.422.220.453.010.590
D12.776.422.220.453.491.360
Unique ID
D065727
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D065727
Scope Note
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE
Entry Term(s)
CYP2C8
CYPIIC8
Cytochrome P450 MP-20
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
S-Mephenytoin 4-Hydroxylase
Registry Number
EC 1.14.14.1
Previous Indexing
Aryl Hydrocarbon Hydroxylases (2002-2014)
Public MeSH Note
2015
History Note
2015
Entry Combination
antagonists & inhibitors:Cytochrome P-450 CYP2C8 Inhibitors
Date Established
2015/01/01
Date of Entry
2014/06/26
Revision Date
2016/05/27
Cytochrome P-450 CYP2C8 Preferred
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