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Cytochrome P-450 CYP2B1 MeSH Descriptor Data 2022


MeSH Heading
Cytochrome P-450 CYP2B1
Tree Number(s)
D08.244.453.005.550
D08.244.453.491.313
D08.811.682.690.708.170.010.550
D08.811.682.690.708.170.450.313
D12.776.422.220.453.010.550
D12.776.422.220.453.491.313
Unique ID
D019362
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019362
Annotation
do not confuse with other cytochrome P-450 CYP's
Scope Note
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Entry Term(s)
7-Benzyloxyresorufin O-Dealkylase
7-Pentylresorufin O-Depentylase
BROD
Benzyloxyresorufin O-Dealkylase
CYP 2B1
CYP2B1
Cytochrome P450 2B1
PROD
Pentoxyresorufin O-Dealkylase
Registry Number
EC 1.14.14.1
Previous Indexing
Cytochrome P-450 (1985-1996)
Oxidoreductases (1985-1996)
Public MeSH Note
97; PENTOXYRESORUFIN O-DEALKYLASE was indexed under CYTOCHROME P-450 & OXIDOREDUCTASES 1985-96
Online Note
use CYTOCHROME P-450 CYP2B1 (NM) to search PENTOXYRESORUFIN O-DEALKYLASE 1985-96
History Note
97; was PENTOXYRESORUFIN O-DEALKYLASE (NM) 1985-96
Date Established
1997/01/01
Date of Entry
1996/06/13
Revision Date
2016/05/27
Cytochrome P-450 CYP2B1 Preferred
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