MeSH Browser

MeSH Heading: 1-Pyrroline-5-Carboxylate Dehydrogenase
Tree Number(s): D08.811.682.662.693
Unique ID: D050842
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050842
Scope Note: An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyperprolinemia II.
Entry Term(s): Delta(1)-Pyrroline-5-Carboxylate Dehydrogenase; GGS Dehydrogenase; Glutamic-Gamma-Semialdehyde Dehydrogenase; Glutamyl-Gamma-Semialdehyde Dehydrogenase; NADP+ Specific 8-Glutamate Semialdehyde Dehydrogenase
Registry Numbers: EC 1.2.1.88
Related Numbers: 9054-82-4
Public MeSH Note: 2006; 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE was indexed under AMINE OXIDOREDUCTASES 1981-2004
History Note: 2006(1981)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/06/02

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adverse effects (AE)

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chemistry (CH)

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standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

1-Pyrroline-5-Carboxylate Dehydrogenase MeSH Descriptor Data 2025