MeSH Browser

MeSH Heading: Prostaglandin-Endoperoxide Synthases
Tree Number(s): D08.811.600.720; D08.811.682.690.708.715
Unique ID: D011451
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011451
Scope Note: Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
Entry Term(s): Arachidonic Acid Cyclooxygenase; Cyclo-Oxygenase; Cyclooxygenase; Cyclooxygenases; Fatty Acid Cyclo-Oxygenase; Hydroperoxide Cyclase; PGH Synthase; PGH2 Synthetase; Prostaglandin Cyclo-Oxygenase; Prostaglandin Cyclooxygenase; Prostaglandin Endoperoxide Synthetase; Prostaglandin G-H Synthase; Prostaglandin H Synthase; Prostaglandin H2 Synthetase; Prostaglandin Synthase; Prostaglandin Synthetase; Prostaglandin-Endoperoxide Synthase
Registry Number: EC 1.14.99.1
CAS Type 1 Name: (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase
NLM Classification #: QU 140
Previous Indexing: Hydroxylases (1974-1977); Multienzyme Complexes (1973-1974); Oxygenases (1971-1973); Prostaglandins (1971-1974)
Public MeSH Note: 2006; see PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1978-2005, see PROSTAGLANDIN SYNTHASE 1978-1991, see under HYDROXYLASES 1975-1977
History Note: 2006(1992);
Entry Combination: antagonists & inhibitors:Cyclooxygenase Inhibitors
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2005/06/30

Entry Combination: antagonists & inhibitors:Cyclooxygenase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Multienzyme Complexes [D08.811.600]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Oxygenases [D08.811.682.690]
      - Mixed Function Oxygenases [D08.811.682.690.708]
        
        Benzoate 4-Monooxygenase [D08.811.682.690.708.062]
        
        Catechol Oxidase [D08.811.682.690.708.125]
        
        Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
        
        Dopamine beta-Hydroxylase [D08.811.682.690.708.292]
        
        Fatty Acid Desaturases [D08.811.682.690.708.392]
        
        gamma-Butyrobetaine Dioxygenase [D08.811.682.690.708.401]
        
        Heme Oxygenase (Decyclizing) [D08.811.682.690.708.410]
        
        4-Hydroxybenzoate-3-Monooxygenase [D08.811.682.690.708.425]
        
        Kynurenine 3-Monooxygenase [D08.811.682.690.708.557]
        
        Phenylalanine Hydroxylase [D08.811.682.690.708.601]
        
        Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase [D08.811.682.690.708.660]
        
        Prolyl Hydroxylases [D08.811.682.690.708.694]
        
        Prostaglandin-Endoperoxide Synthases [D08.811.682.690.708.715]
        
        Squalene Monooxygenase [D08.811.682.690.708.749]
        
        Trans-Cinnamate 4-Monooxygenase [D08.811.682.690.708.826]
        
        Tryptophan Hydroxylase [D08.811.682.690.708.870]
        
        Tyrosine 3-Monooxygenase [D08.811.682.690.708.923]
        
        Vitamin K Epoxide Reductases [D08.811.682.690.708.961]

Prostaglandin-Endoperoxide Synthases Preferred

Concept UI: M0017803
Registry Number: EC 1.14.99.1
Scope Note: Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
Terms: Prostaglandin-Endoperoxide Synthases Preferred Term
Term UI T641056
Date05/19/2005
LexicalTag NON
ThesaurusID NLM (2006); Prostaglandin-Endoperoxide Synthase
Term UI T033807
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Cyclooxygenase
Term UI T033804
Date05/31/1983
LexicalTag NON
ThesaurusID UNK (19XX); Cyclooxygenases
Term UI T641057
Date05/19/2005
LexicalTag NON
ThesaurusID NLM (2006); Fatty Acid Cyclo-Oxygenase
Term UI T033805
Date05/09/1977
LexicalTag NON
ThesaurusID UNK (19XX); Hydroperoxide Cyclase
Term UI T033806
Date11/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); PGH Synthase
Term UI T033812
Date06/05/1985
LexicalTag NON
ThesaurusID UNK (19XX); PGH2 Synthetase
Term UI T033813
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin Cyclo-Oxygenase
Term UI T033817
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin Cyclooxygenase
Term UI T033814
Date11/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin Endoperoxide Synthetase
Term UI T033818
Date05/31/1983
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin G-H Synthase
Term UI T033808
Date07/19/1988
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin H Synthase
Term UI T033809
Date06/05/1985
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin H2 Synthetase
Term UI T033810
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Prostaglandin Synthase
Term UI T033811
Date04/03/1991
LexicalTag NON
ThesaurusID NLM (1992); Prostaglandin Synthetase
Term UI T033815
Date04/03/1991
LexicalTag NON
ThesaurusID NLM (1992); Arachidonic Acid Cyclooxygenase
Term UI T033803
Date11/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); Cyclo-Oxygenase
Term UI T033816
Date06/25/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Prostaglandin-Endoperoxide Synthases MeSH Descriptor Data 2024