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Prostaglandin-Endoperoxide Synthases MeSH Descriptor Data 2025


MeSH Heading
Prostaglandin-Endoperoxide Synthases
Tree Number(s)
D08.811.600.720
D08.811.682.690.708.715
Unique ID
D011451
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011451
Scope Note
Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
Entry Term(s)
Arachidonic Acid Cyclooxygenase
Cyclo-Oxygenase
Cyclooxygenase
Cyclooxygenases
Fatty Acid Cyclo-Oxygenase
Hydroperoxide Cyclase
PGH Synthase
PGH2 Synthetase
Prostaglandin Cyclo-Oxygenase
Prostaglandin Cyclooxygenase
Prostaglandin Endoperoxide Synthetase
Prostaglandin G-H Synthase
Prostaglandin H Synthase
Prostaglandin H2 Synthetase
Prostaglandin Synthase
Prostaglandin Synthetase
Prostaglandin-Endoperoxide Synthase
Registry Numbers
EC 1.14.99.1
CAS Type 1 Name
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase
NLM Classification #
QU 140
Previous Indexing
Hydroxylases (1974-1977)
Multienzyme Complexes (1973-1974)
Oxygenases (1971-1973)
Prostaglandins (1971-1974)
Public MeSH Note
2006; see PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1978-2005, see PROSTAGLANDIN SYNTHASE 1978-1991, see under HYDROXYLASES 1975-1977
History Note
2006(1992);
Entry Combination
antagonists & inhibitors:Cyclooxygenase Inhibitors
Date Established
1978/01/01
Date of Entry
1974/11/11
Revision Date
2005/06/30
Prostaglandin-Endoperoxide Synthases Preferred
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