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Insulysin MeSH Descriptor Data 2025


MeSH Heading
Insulysin
Tree Number(s)
D08.811.277.656.300.480.300
D08.811.277.656.675.374.300
Unique ID
D007339
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007339
Scope Note
An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56.
Entry Term(s)
Insulin Protease
Insulin Proteinase
Insulin-Degrading Enzyme
Insulinase
Registry Numbers
EC 3.4.24.56
Public MeSH Note
97; was INSULINASE 1963-96 (see under PEPTIDE HYDROLASES 1975-90, see under PEPTIDE PEPTIDOHYDROLASES 1963-74)
Online Note
search ENDOPEPTIDASES 1966-74
History Note
97; was INSULINASE 1963-96 (see under PEPTIDE HYDROLASES 1975-90, see under ENDOPEPTIDASES 1963-74)
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2003/07/09
Insulysin Preferred
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