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Interleukin-1 MeSH Descriptor Data 2025


MeSH Heading
Interleukin-1
Tree Number(s)
D12.644.276.374.465.010
D12.644.276.374.500.400
D12.776.467.374.465.010
D12.776.467.374.500.400
D23.529.374.465.131
D23.529.374.500.400
Unique ID
D007375
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007375
Scope Note
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Entry Term(s)
Epidermal Cell Derived Thymocyte-Activating Factor
IL-1
Interleukin I
Lymphocyte-Activating Factor
Macrophage Cell Factor
T Helper Factor
Registry Numbers
0
Previous Indexing
Lymphocytes (1966-1971)
Lymphocyte Transformation (1972-1982)
Lymphokines (1974-1982)
Macrophages (1966-1982)
Toxins (1966-1973)
See Also
Receptors, Interleukin-1
Public MeSH Note
1990; see INTERLEUKIN 1 1983-1989
History Note
1990(1983)
Date Established
1983/01/01
Date of Entry
1982/04/29
Revision Date
2015/04/15
Interleukin-1 Preferred
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