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Ryanodine Receptor Calcium Release Channel MeSH Descriptor Data 2024


MeSH Heading
Ryanodine Receptor Calcium Release Channel
Tree Number(s)
D12.776.157.530.400.150.800
D12.776.210.500.800
D12.776.543.550.450.150.800
D12.776.543.585.400.150.800
Unique ID
D019837
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019837
Scope Note
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Entry Version
RYANODINE RECEPT CALCIUM RELEASE CHANNEL
Entry Term(s)
Ca Release Channel-Ryanodine Receptor
Calcium-Ryanodine Receptor Complex
Receptor, Ryanodine
RyR1
RyR2
RyR3
Ryanodine Receptor
Ryanodine Receptor 1
Ryanodine Receptor 2
Ryanodine Receptor 3
Ryanodine Receptors
Previous Indexing
Calcium Channels (1988-1997)
Muscle Proteins (1993-1997)
Receptors, Cholinergic (1985-1992)
Public MeSH Note
98; CALCIUM-RYANODINE RECEPTOR COMPLEX (now RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL) was indexed under CALCIUM CHANNELS 1988-97, MUSCLE PROTEINS 1993-97, & RECEPTORS, CHOLINERGIC 1985-92
History Note
98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97
Entry Combination
agonists:Calcium Channel Agonists
antagonists & inhibitors:Calcium Channel Blockers
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2016/07/01
Ryanodine Receptor Calcium Release Channel Preferred
Ryanodine Receptors Broader
Ryanodine Receptor 2 Narrower
Ryanodine Receptor 3 Narrower
Ryanodine Receptor 1 Narrower
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