Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Entry Term(s)
Thioredoxin
Thioredoxin 1
Thioredoxin 2
Thioredoxin-1
Thioredoxin-2
Registry Number
52500-60-4
CAS Type 1 Name
Thioredoxins
NLM Classification #
QU 55
Previous Indexing
Bacterial Proteins (1968-1974)
Public MeSH Note
2008; see THIOREDOXIN 1991, see BACTERIAL PROTEINS 1975-1990; THIOREDOXIN 2 was indexed under THIOREDOXIN & MEMBRANE PROTEINS 1997-2006
Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
