MeSH Browser

MeSH Heading: Ubiquitin-Protein Ligases
Tree Number(s): D08.811.464.938.750
Unique ID: D044767
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044767
Annotation: UBIQUITIN-PROTEIN LIGASE COMPLEXES is also available
Scope Note: A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
Entry Term(s): E3 Ligase; E3 Ubiquitin Ligase; Ubiquitin Ligase E3; Ubiquitin-Protein Ligase; Ubiquitin-Protein Ligase E3
Registry Numbers: EC 2.3.2.27
Related Numbers: EC 2.3.2.26
Previous Indexing: Ligases (1983-2003)
Public MeSH Note: 2004; UBIQUITIN-PROTEIN LIGASE was indexed under LIGASES 1983-2003; E3 UBIQUITIN LIGASE was indexed under LIGASES 1993-2003
History Note: 2004; use UBIQUITIN-PROTEIN LIGASE (NM) 1983-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0446168
Registry Numbers: EC 2.3.2.27
Related Numbers: EC 2.3.2.26
Scope Note: A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
Terms: Ubiquitin-Protein Ligases Preferred Term
Term UI T533941
Date02/27/2003
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitin Ligase E3
Term UI T529757
Date01/04/2003
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitin-Protein Ligase E3
Term UI T533942
Date02/27/2003
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitin-Protein Ligase
Term UI T145800
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); E3 Ubiquitin Ligase
Term UI T242487
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); E3 Ligase
Term UI T461704
Date09/15/2001
LexicalTag NON
ThesaurusID NLM (2004)

Ubiquitin-Protein Ligases MeSH Descriptor Data 2024