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Steroid 16-alpha-Hydroxylase MeSH Descriptor Data 2025
A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.
Entry Term(s)
16-alpha Hydroxylase
16alpha-Hydroxylase
Cytochrome P-450(16 alpha)
Estradiol 16-alpha Hydroxylase
Estrogen 16-alpha Hydroxylase
Estrone 16-alpha Hydroxylase
Estrone-3-sulfate 16-alpha Hydroxylase
Progesterone 16 alpha-Hydroxylase
Progesterone 16-alpha-Hydroxylase
Progesterone-16-alpha-Hydroxylase
Steroid 16alpha-Hydroxylase
Testosterone 16-alpha Hydroxylase
Testosterone 16alpha Hydroxylase
Registry Numbers
EC 1.14.14.1
Previous Indexing
Hydroxylases (1966-2002)
Public MeSH Note
2003; PROGESTERONE 16 ALPHA-HYDROXYLASE was indexed under STEROID HYDROXYLASES 1977-2002
History Note
2003; use PROGESTERONE 16 ALPHA-HYDROXYLASE (NM) 1977-2002
A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.