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Histocompatibility Antigens Class I MeSH Descriptor Data 2022


MeSH Heading
Histocompatibility Antigens Class I
Tree Number(s)
D12.776.395.550.489
D12.776.543.550.439
D23.050.301.500.100
D23.050.705.552.100
Unique ID
D015395
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015395
Annotation
human & animal
Scope Note
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
Entry Term(s)
Class I Antigen
Class I Antigens
Class I Histocompatibility Antigen
Class I Histocompatibility Antigens
Class I Human Antigens
Class I MHC Protein
Class I MHC Proteins
Class I Major Histocompatibility Antigen
Class I Major Histocompatibility Antigens
Class I Major Histocompatibility Molecules
Human Class I Antigens
MHC Class I Molecule
MHC Class I Molecules
MHC-I Molecules
MHC-I Peptide
MHC-I Peptides
Registry Number
0
Previous Indexing
HLA Antigens (1978-1988)
Histocompatibility Antigens (1973-1988)
See Also
Genes, MHC Class I
Public MeSH Note
89
History Note
89
Date Established
1988/01/01
Date of Entry
1988/06/06
Revision Date
2020/05/27
Histocompatibility Antigens Class I Preferred
Human Class I Antigens Narrower
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