MeSH Browser

MeSH Heading: Steroid Hydroxylases
Tree Number(s): D08.244.453.915; D08.811.682.690.708.170.915; D12.776.422.220.453.915
Unique ID: D013250
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013250
Annotation: general; prefer specifics
Scope Note: Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism.
Entry Term(s): Steroid Hydroxylase; Steroid Monooxygenases
Previous Indexing: Hydroxylases (1966-1972)
Public MeSH Note: 73
History Note: 73
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Cytochromes [D08.244]
  - Cytochrome P-450 Enzyme System [D08.244.453]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Oxygenases [D08.811.682.690]
      - Mixed Function Oxygenases [D08.811.682.690.708]
        
        Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
        
        Cytochrome P-450 CYP2J2 [D08.811.682.690.708.170.005]
        
        Aryl Hydrocarbon Hydroxylases [D08.811.682.690.708.170.010]
        
        Camphor 5-Monooxygenase [D08.811.682.690.708.170.012]
        
        Cytochrome P450 Family 1 [D08.811.682.690.708.170.020]
        
        Cytochrome P450 Family 11 [D08.811.682.690.708.170.425]
        
        Cytochrome P450 Family 12 [D08.811.682.690.708.170.438]
        
        Cytochrome P450 Family 17 [D08.811.682.690.708.170.444]
        
        Cytochrome P450 Family 19 [D08.811.682.690.708.170.447]
        
        Cytochrome P450 Family 2 [D08.811.682.690.708.170.450]
        
        Cytochrome P450 Family 21 [D08.811.682.690.708.170.463]
        
        Cytochrome P450 Family 24 [D08.811.682.690.708.170.469]
        
        Cytochrome P450 Family 26 [D08.811.682.690.708.170.485]
        
        Cytochrome P450 Family 27 [D08.811.682.690.708.170.493]
        
        Cytochrome P450 Family 3 [D08.811.682.690.708.170.495]
        
        Cytochrome P450 Family 4 [D08.811.682.690.708.170.496]
        
        Cytochrome P450 Family 46 [D08.811.682.690.708.170.497]
        
        Cytochrome P450 Family 51 [D08.811.682.690.708.170.499]
        
        Cytochrome P450 Family 6 [D08.811.682.690.708.170.880]
        
        Cytochrome P450 Family 7 [D08.811.682.690.708.170.890]
        
        Cytochrome P450 Family 8 [D08.811.682.690.708.170.900]
        
        Steroid Hydroxylases [D08.811.682.690.708.170.915]
        
        Cholesterol 24-Hydroxylase [D08.811.682.690.708.170.915.025]
        
        Cytochrome P-450 CYP11B2 [D08.811.682.690.708.170.915.050]
        
        Aromatase [D08.811.682.690.708.170.915.099]
        
        Cholestanetriol 26-Monooxygenase [D08.811.682.690.708.170.915.150]
        
        Cholesterol 7-alpha-Hydroxylase [D08.811.682.690.708.170.915.200]
        
        Cholesterol Side-Chain Cleavage Enzyme [D08.811.682.690.708.170.915.212]
        
        25-Hydroxyvitamin D3 1-alpha-Hydroxylase [D08.811.682.690.708.170.915.400]
        
        Steroid 12-alpha-Hydroxylase [D08.811.682.690.708.170.915.730]
        
        Steroid 16-alpha-Hydroxylase [D08.811.682.690.708.170.915.737]
        
        Steroid 17-alpha-Hydroxylase [D08.811.682.690.708.170.915.748]
        
        Steroid 11-beta-Hydroxylase [D08.811.682.690.708.170.915.750]
        
        Steroid 21-Hydroxylase [D08.811.682.690.708.170.915.760]
        
        Sterol 14-Demethylase [D08.811.682.690.708.170.915.880]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Hemeproteins [D12.776.422]
    - Cytochromes [D12.776.422.220]
      - Cytochrome P-450 Enzyme System [D12.776.422.220.453]
        
        Cytochrome P-450 CYP2J2 [D12.776.422.220.453.005]
        
        Aryl Hydrocarbon Hydroxylases [D12.776.422.220.453.010]
        
        Camphor 5-Monooxygenase [D12.776.422.220.453.012]
        
        Cytochrome P450 Family 1 [D12.776.422.220.453.100]
        
        Cytochrome P450 Family 11 [D12.776.422.220.453.484]
        
        Cytochrome P450 Family 12 [D12.776.422.220.453.485]
        
        Cytochrome P450 Family 17 [D12.776.422.220.453.487]
        
        Cytochrome P450 Family 19 [D12.776.422.220.453.489]
        
        Cytochrome P450 Family 2 [D12.776.422.220.453.491]
        
        Cytochrome P450 Family 21 [D12.776.422.220.453.493]
        
        Cytochrome P450 Family 24 [D12.776.422.220.453.496]
        
        Cytochrome P450 Family 26 [D12.776.422.220.453.498]
        
        Cytochrome P450 Family 27 [D12.776.422.220.453.499]
        
        Cytochrome P450 Family 3 [D12.776.422.220.453.860]
        
        Cytochrome P450 Family 4 [D12.776.422.220.453.870]
        
        Cytochrome P450 Family 46 [D12.776.422.220.453.875]
        
        Cytochrome P450 Family 51 [D12.776.422.220.453.878]
        
        Cytochrome P450 Family 6 [D12.776.422.220.453.880]
        
        Cytochrome P450 Family 7 [D12.776.422.220.453.890]
        
        Cytochrome P450 Family 8 [D12.776.422.220.453.900]
        
        Steroid Hydroxylases [D12.776.422.220.453.915]
        
        Cholesterol 24-Hydroxylase [D12.776.422.220.453.915.025]
        
        Cytochrome P-450 CYP11B2 [D12.776.422.220.453.915.050]
        
        Aromatase [D12.776.422.220.453.915.099]
        
        Cholestanetriol 26-Monooxygenase [D12.776.422.220.453.915.150]
        
        Cholesterol 7-alpha-Hydroxylase [D12.776.422.220.453.915.200]
        
        Cholesterol Side-Chain Cleavage Enzyme [D12.776.422.220.453.915.212]
        
        25-Hydroxyvitamin D3 1-alpha-Hydroxylase [D12.776.422.220.453.915.400]
        
        Steroid 12-alpha-Hydroxylase [D12.776.422.220.453.915.730]
        
        Steroid 16-alpha-Hydroxylase [D12.776.422.220.453.915.737]
        
        Steroid 17-alpha-Hydroxylase [D12.776.422.220.453.915.748]
        
        Steroid 11-beta-Hydroxylase [D12.776.422.220.453.915.750]
        
        Steroid 21-Hydroxylase [D12.776.422.220.453.915.760]
        
        Sterol 14-Demethylase [D12.776.422.220.453.915.880]

Steroid Hydroxylases Preferred

Steroid Hydroxylases MeSH Descriptor Data 2024