MeSH Browser

MeSH Heading: De Lange Syndrome
Tree Number(s): C10.597.606.360.210; C16.131.077.272; C16.131.260.210; C16.320.180.210
Unique ID: D003635
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003635
Scope Note: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)
Entry Term(s): Brachmann-De Lange Syndrome; CdLS, X-Linked; CdLS2; Cornelia De Lange Syndrome; Cornelia de Lange Syndrome 1; Cornelia de Lange Syndrome 2; Cornelia de Lange Syndrome 3; Cornelia de Lange Syndrome, X-Linked; De Lange's Syndrome; Typus Degenerativus Amstelodamensis
See Also: Intellectual Disability
Public MeSH Note: 2000; see DE LANGE'S SYNDROME 1966-1999
History Note: 2000(1964)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/05/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0005689
Scope Note: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)
Terms: De Lange Syndrome Preferred Term
Term UI T365394
Date11/03/1999
LexicalTag EPO
ThesaurusID; Cornelia De Lange Syndrome
Term UI T365403
Date11/03/1999
LexicalTag EPO
ThesaurusID; Brachmann-De Lange Syndrome
Term UI T365402
Date11/03/1999
LexicalTag EPO
ThesaurusID; Typus Degenerativus Amstelodamensis
Term UI T365404
Date11/03/1999
LexicalTag NON
ThesaurusID; De Lange's Syndrome
Term UI T010602
Date01/01/1999
LexicalTag EPO
ThesaurusID NLM (1964)

Concept UI: M0552970
Terms: Cornelia de Lange Syndrome 2 Preferred Term
Term UI T782912
Date12/28/2010
LexicalTag EPO
ThesaurusID; CdLS, X-Linked
Term UI T825868
Date07/10/2012
LexicalTag ABX
ThesaurusID OMIM (2013); CdLS2
Term UI T825869
Date07/10/2012
LexicalTag ABB
ThesaurusID OMIM (2013); Cornelia de Lange Syndrome, X-Linked
Term UI T782913
Date12/28/2010
LexicalTag EPO
ThesaurusID

De Lange Syndrome MeSH Descriptor Data 2024