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De Lange Syndrome MeSH Descriptor Data 2022


MeSH Heading
De Lange Syndrome
Tree Number(s)
C10.597.606.360.210
C16.131.077.272
C16.131.260.210
C16.320.180.210
Unique ID
D003635
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003635
Scope Note
A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)
Entry Term(s)
Brachmann-De Lange Syndrome
CdLS, X-Linked
CdLS2
Cornelia De Lange Syndrome
Cornelia de Lange Syndrome 1
Cornelia de Lange Syndrome 2
Cornelia de Lange Syndrome 3
Cornelia de Lange Syndrome, X-Linked
De Lange's Syndrome
Typus Degenerativus Amstelodamensis
See Also
Intellectual Disability
Public MeSH Note
2000; see DE LANGE'S SYNDROME 1966-1999
History Note
2000(1964)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2019/05/17
De Lange Syndrome Preferred
Cornelia de Lange Syndrome 2 Narrower
Cornelia de Lange Syndrome 3 Narrower
Cornelia de Lange Syndrome 1 Narrower
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