MeSH Browser

MeSH Heading: Donohue Syndrome
Tree Number(s): C05.660.207.325; C16.131.077.313; C16.320.215; C18.452.394.750.654; C19.246.537
Unique ID: D056731
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D056731
Scope Note: Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic FACIES; HIRSUTISM; VIRILIZATION; multiple endocrine abnormalities, and early death.
Entry Term(s): Leprechaunism; Mendenhall Syndrome; Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities; Rabson-Mendenhall Syndrome
Previous Indexing: Abnormalities, Multiple (2002-2009); Acanthosis Nigricans (2002-2009); Diabetes Mellitus (2000-2009)
See Also: Insulin Resistance; Receptor, Insulin
Public MeSH Note: 2010
History Note: 2010
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2012/07/03

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Donohue Syndrome MeSH Descriptor Data 2024