MeSH Browser

MeSH Heading: Fibroblast Growth Factors
Tree Number(s): D12.644.276.624; D12.776.467.624; D23.529.624
Unique ID: D005346
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005346
Scope Note: A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
Entry Term(s): DNA Synthesis Factor; Fibroblast Growth Factor; Fibroblast Growth Regulatory Factor
Registry Numbers: 62031-54-3
CAS Type 1 Name: Fibroblast growth factor
NLM Classification #: QU 107
Previous Indexing: Fibroblasts (1974-1983); Growth Substances (1974-1983); Mitogens (1974-1983); Nerve Tissue Proteins (1974-1983); Peptides (1974-1983); Pituitary Hormones (1974-1983)
See Also: Receptors, Fibroblast Growth Factor
Public MeSH Note: 2001; see FIBROBLAST GROWTH FACTOR 1984-2001
History Note: 2001(1984)
Date Established: 1984/01/01
Date of Entry: 1983/05/31
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0008437
Registry Numbers: 62031-54-3
Scope Note: A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
Terms: Fibroblast Growth Factors Preferred Term
Term UI T440527
Date03/23/2001
LexicalTag NON
ThesaurusID NLM (2002); DNA Synthesis Factor
Term UI T016319
Date09/16/1987
LexicalTag NON
ThesaurusID UNK (19XX); Fibroblast Growth Factor
Term UI T016320
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1984); Fibroblast Growth Regulatory Factor
Term UI T016321
Date05/31/1983
LexicalTag NON
ThesaurusID UNK (19XX)

Fibroblast Growth Factors MeSH Descriptor Data 2024