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Huntington Disease MeSH Descriptor Data 2025


MeSH Heading
Huntington Disease
Tree Number(s)
C10.228.140.079.545
C10.228.140.380.278
C10.228.662.262.249.750
C10.574.500.497
C16.320.400.430
F03.615.250.400
F03.615.400.390
Unique ID
D006816
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006816
Scope Note
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Entry Version
HUNTINGTON DIS
Entry Term(s)
Akinetic-Rigid Variant of Huntington Disease
Chorea, Chronic Progressive Hereditary (Huntington)
Chronic Progressive Hereditary Chorea (Huntington)
Huntington Chorea
Huntington Chronic Progressive Hereditary Chorea
Huntington Disease, Akinetic-Rigid Variant
Huntington Disease, Juvenile
Huntington Disease, Juvenile-Onset
Huntington Disease, Late Onset
Huntington's Chorea
Huntington's Disease
Juvenile Huntington Disease
Juvenile-Onset Huntington Disease
Late-Onset Huntington Disease
Progressive Chorea, Chronic Hereditary (Huntington)
Progressive Chorea, Hereditary, Chronic (Huntington)
NLM Classification #
WL 359.5
Public MeSH Note
2000; see HUNTINGTON'S DISEASE 1993-1999; for HUNTINGTON DISEASE see HUNTINGTON'S DISEASE 1993-1999, see HUNTINGTON CHOREA 1977-1992, see CHOREA, HEREDITARY 1963-1976
History Note
2000(1963)
Date Established
2000/01/01
Date of Entry
1999/01/01
Revision Date
2015/06/30
Huntington Disease Preferred
Juvenile Huntington Disease Narrower
Akinetic-Rigid Variant of Huntington Disease Narrower
Huntington Disease, Late Onset Narrower
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