A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Entry Term(s)
PIAS Proteins
PIAS1 Protein
PIAS1 Protein Inhibitor of Activated STAT
PIAS2 Protein Inhibitor of Activated STAT
PIAS3 Protein Inhibitor of Activated STAT
PIAS4 Protein Inhibitor of Activated STAT
Registry Numbers
0
Public MeSH Note
2006; PROTEIN INHIBITORS OF ACTIVATED STAT was indexed under PROTEINS 1998-2005
A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.