MeSH Browser

MeSH Heading: Replication Protein C
Tree Number(s): D08.811.277.040.013.500.438; D08.811.277.040.025.024.438; D12.776.157.025.750.438; D12.776.260.702
Unique ID: D051818
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051818
Scope Note: A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Entry Term(s): Activator 1 Protein; Activator 1 Protein, 145 kDa Subunit; Activator 1 Protein, 36 kDa Subunit; Activator 1 Protein, 37 kDa Subunit; Activator 1 Protein, 38 kDa Subunit; Activator 1 Protein, 40 kDa Subunit; Activator 1 p40; Replication Factor C; Replication Factor C, Subunit 1; Replication Factor C, Subunit 2; Replication Factor C, Subunit 3; Replication Factor C, Subunit 4; Replication Factor C, Subunit 5; Replication Protein C, Subunit 1; Replication Protein C, Subunit 2; Replication Protein C, Subunit 3; Replication Protein C, Subunit 4; Replication Protein C, Subunit 5
Public MeSH Note: 2006; see REPLICATION FACTOR C 2006, REPLICATION PROTEIN C was indexed under DNA-BINDING PROTEINS 1992-2005
History Note: 2006(1992)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/03/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0199685
Terms: Replication Protein C, Subunit 2 Preferred Term
Term UI T664900
Date01/23/2006
LexicalTag NON
ThesaurusID NLM (2007); Activator 1 p40
Term UI T229690
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Activator 1 Protein, 40 kDa Subunit
Term UI T456914
Date08/10/2001
LexicalTag NON
ThesaurusID NLM (2006); Replication Factor C, Subunit 2
Term UI T633245
Date03/14/2005
LexicalTag NON
ThesaurusID NLM (2006)

Replication Protein C MeSH Descriptor Data 2024